The goal of Mosa Joints is to provide a solution that can effectively regenerate natural joint tissue, improve long-term outcomes, and reduce the need for invasive surgeries.
Our solution is a 3D printed scaffold (supporting structure) that includes an artificial environment for stem cells embedded in a hydrogel. This scaffold is designed so that the stem cells move to the outer layers and develop into either cartilage or bone cells. Experiments show that this scaffold creates tissue that looks and behaves like natural joint tissue, with clear differences between the bone and cartilage parts and similar biomechanics. This new implant could be used in joints damaged by injuries or conditions like osteoarthritis, helping them to heal by growing back natural tissue.
Osteoarthritis is the leading cause of disability in older adults, severely impacting quality of life. In 2020, 595 million people (7.6% of the global population) suffered from osteoarthritis. The knee is the most affected joint, with projections estimating 642 million people will suffer from knee osteoarthritis by 2050.
This project will focus on gathering evidence through an in-depth histological analysis of collagen characterization in osteochondral regenerated tissue. It will also advance competitor analysis, IP assessment, and value proposition, addressing questions regarding clinical application and business potential.