At Biosonics, we are tackling one of the biggest challenges in life sciences: seeing what cells are doing deep inside organs, in real time, without invasive procedures.
Today, the gold standard for cellular imaging is fluorescent microscopy. While powerful, it cannot see deeper than one millimeter due to light scattering. This limitation means that researchers have to rely on destructive and time consuming methods such as biopsies or tissue clearing to image. As a result, there is no dynamic, non-invasive way to follow how diseases progress or how therapies act on cells within their natural environment.
Biosonics solves this by combining innovative ultrasound techniques with a new class of molecular probes that allow cells to interface with sound waves. These probes are genetically encodable and can be expressed by cells, making them the acoustic equivalent of green fluorescent protein. This allows us to visualize cells and gene expression in 3D, in real time, and deep inside living organs, noninvasively, and reveal biology that was previously inaccessible.