Cryopreserved Jammed Architectures of Microparticles for personalized medicine
Hydrogels are promising carriers for drugs and bioactive compounds. However, standard hydrogel formulations are hard to dose and have a limited shelf-life. CryoJAM is a new technology that allows for the patterning of hydrogel microparticle constructs. The granular hydrogels are printable, facilitating a controlled and personalizable formulation of multiple active components within a single tablet or capsule. Additionally, CryoJAM has developed technology to enable the long-term storage of active hydrogel microparticles and constructs at room temperature. This unique feature greatly enhances the potential commercial application of bioactive hydrogel formulations. In this project, we will validate the production of several granular hydrogel based tablets with multiple bioactive compounds, and will establish a quality control workflow for tablet standards of pharmacopoieia.