Technological innovations are needed more than ever to keep health care affordable, qualitative, and staffed in the long term. However, the route to the market is very complex and difficult for MedTech spin-offs. The Knowledge Transfer Offices (KTO) of TU Delft, TU Eindhoven, University of Twente, and Wageningen University & Research are building a national and open program, together with the KTOs of Erasmus MC, RadboudUMC, and Maastricht UMC, as well as VC fund Innovation Industries.